Medicinally it mainly refers to the dried leaves of Morus alba L., which is a plant in the family of Moraceae. And other names of it include White Mulberry Leaf, Folium Mori, mulberry tree leaves, and so on. In China it is distributed all over the country, wild or cultivated. When used as medicine it is usually harvested after the first frost. And following steps are to remove the impurities and dry in the sun. It is used raw or baked with honey.Traditionally the one after frost, called “frosted or winter mulberry leaves”, is considered with better medicinal uses.Main chemical compositions are steroids and triterpenoids, flavonoids and its glycosides, coumarin and its glycosides, volatile oil, amino acids and small peptides, alkaloids, and organic acids and other compounds. Steroids and triterpenoids include inokosterone, ecdysterone, stigmasterol, campesterol, lupeol, β-sitosterol and its acetyl derivative, β-amyrin, and the like. Flavonoids and its glycosides include rutin, quercetin, isoquercitrin, moracetin, kuwanon I, and more. Coumarin and its glycosides include bergaten, umbelliferone, scopoletin, scopolin, hydroxycoumarin, and so on. Volatile oil include acetic acid, propionic acid, butyric acid, iso-butyric acid, valeric acid, isovaleric acid, caproic acid, methyl salicylate, guaiacol, O-cresol, m-cresol, p-cresol, eugenol, etc. Amino acids and small peptides include glutamic acid, aspartic acid, alanine, glycine, γ-aminobutyric acid, pipecolic acid, 5-hydroxy- pipecolic acid, proline, arginine, sarcosine, leucine, isoleucine, tyrosine, valine, tryptophan, asparagine, glutamine, serine, lysine, glutathione, etc. Alkaloids include adenine, choline, trigonelline, etc. And organic acids and other compounds include chlorogenic acid, fumaric acid, palmitic acid, Ethyl palmitate, folic acid, folinic acid, vitamin C, alkanes, myo-inositol, hemolysin, etc.